Each tablet contains, Echinacea
Organic echinacea herb (Echinacea purpurea) 1140 mg
Organic echinacea root (Echinacea purpurea) 60 mg
Other ingredients: lactose, starch, magnesium stearate
The adult daily dose of Echinaforce® Forte corresponds to 1200 mg to 3600 mg
of fresh Echinacea.
Take 1 to 3 tablets daily, 15 minutes before meals.
Long before the coming of the
European settlers, the native Americans used Echinacea (also called Purple
Cone Flower) to treat a variety of problems, from infections to snake bites.
In the United States, Echinacea was popularized by the eclectic physicians`
movement in the 19th Century. After that, its use was almost forgotten until
the 1980`s. In Europe, however, Echinacea was popular with the medical world
from the beginning of the Century and has been the subject of numerous
clinical studies. Today, Echinacea is the most widely sold medicinal herb in
Actions and pharmacology
In vitro studies have allowed the
discovery of Echinacea’s action mechanism: its polysaccharides and
polyacetylenes fractions stimulate the phagocytosis of macrophages and the
production of cytokines like interleukine-1, interleukine-6 (also called
interferon beta), interleukine-10 and TNF alpha factor. This effect shows
Echinacea’s ability to stimulate the immune system in cases of infection.(1)
Chicoric acid and analogues derived from caffeic acid are presently under
investigation for their effect on HIV-1 replication.(2)
Echinacea, particularly the echinacosides and caffeic acid derivatives,
might protect collagen structures against degradation (oxidation) caused by
free radicals. This antioxidant effect is also useful to relieve the
inflammation generated by the immune system during its fight against the
viruses of colds.
Many clinical studies demonstrate
Echinacea’s efficacy as an immune system stimulant.(3-5) According to the
authors of an important meta-analysis (a review of articles on clinical
studies), Echinacea is effective against respiratory infections, especially
if taken as soon as the first symptoms appear.(6)
specifically has also been the subject of conclusive clinical studies. A
double-blind placebo-controlled study was conducted in Sweden on Echinaforce®
tablets. 246 patients suffering from colds took either 6 Echinaforce®<
tablets daily, a special Echinacea preparation (7 times more concentrated),
another form of Echinacea, or a placebo. Echinaforce® and the concentrated
preparation were equally effective in reducing cold symptoms and
significantly more effective than the other Echinacea preparation or the
Another study conducted on 119 patients demonstrated a 60% improvement of
cold symptoms with Echinaforce® tablets compared to a placebo.(8)
A recent study (April 2002) on 48 volunteers showed that Echinacea
significantly increases one of the markers of immune system stimulation:
According to a recent pilot study, an Echinacea extract seems to reduce the
side effects of certain chemotherapy medications.(10)
contraindications and interactions
Contraindication: known allergy to
one of the ingredients or to any flower belonging to the daisy (asteracea)
A few cases of prolonged bleeding time were reported. It is therefore not
recommended to combine echinacea with anticoagulant medications like
Because Echinacea is an immune stimulant, its combination with immuno-suppressive
medications like Methotrexate® or Immuran® is contraindicated. Echinacea is
also not recommended for people suffering from leukemia or other auto-immune
A study conducted in Toronto by the Motherisk Program states that Echinacea
is safe during pregnancy. (11) However, it is always best to consult a
competent health professional.
FLUS and COLDS
Echinacea Lozenges, Usneasan, Drosinula®, Santasapina® Syrup and Lozenges,
Resistasan®, Pulsaralia, Sinna, Arasma
Usneasan, Drosinula®, Santasapina®, Arasma, Resistasan®
Comfrey, Tormentavena®, Molkosan®, Bioforce Cream, Echinacea Cream,
Cystoforce, Golden Rod
1. Burger Ra, Torres AR, Warren RP et al.
Echinacea-induced cytokine by human macrophages. Int J Immunopharmacol
2. Lin Z, Neamati N, Zhao H et al. Chicoric acid analogues as HIV-1
integrase inhibitors. J Med Chem 1999;42(8):1401-14.
3. Gunning K. Echinacea in the treatment and prevention of upper respiratory
tract infections. West J Med 1999;171:198-200.
4. Barrett B, Vohmann M, Calabrese C. Echinacea for upper respiratory
infection. J Fam Pract 1999;48:628-35.
5. Grimm W, Muller HH. A randomized controlled trial of the effect of fluid
extract of Echinacea purpurea on the incidence and severity of colds and
respiratory infections. Am J Med 1999;106:138-43.
6. Barrett B, Vohmann M et Calabrese C. Echinacea for Upper respiratory
infection. J Fam Pract 1999;48(8):628-35.
7. Brinkeborn RM, Shah DV, Degenring FH. Echinaforce® and other Echinacea
fresh plant preparations in the treatment of the common cold. A randomized,
placebo controlled, double-blind clinical trial. Phytomedicine 1999
8. Brinkeborn RM, Shah DV, Geissbühler S, Degenring FH. Echinaforce® dans le
traitement des états grippaux aigus. Schweiz Zschr GanzheitsMedizin
9. Kim LS, Waters RF, Burkholder PM. Immunological activity of larch
arabinogalactan and Echinacea: A preliminary, randomized, double-blind,
placebo-controlled trial. Altern Med Rev 2002 Apr;7(2):138-149
10. Melchart D, Clemm C, Weber B et al. Polysaccharides isolated from
Echinacea purpurea herba cell cultures to counteract undesired effects of
chemotherapy--a pilot study. Phytother Res 2002 Mar;16(2):138-42
11. Gallo M, Sarkar M, Au W et al. Pregnancy outcome following gestational
exposure to echinacea: a prospective controlled study. Arch Intern Med
have not been evaluated by the Food and Drug Administration.
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